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Revian announces patent for LED hair-loss prevention tech

REVIAN Presents Leading Clinical Trial Results for New Hair Loss Treatment

REVIAN Presents Leading Clinical Trial Results for New Hair Loss Treatment

REVIAN Inc – a medical technology company dedicated to stimulating the body’s natural processes to rejuvenate hair and skin with light – is excited to announce that final data from a randomized, double-blind study of the REVIAN RED hair growth system was presented at the 2020 Winter Clinical Dermatology Conference – Hawaii®.

The data is now available on the REVIAN website following the presentation at the conference. In this clinical trial, REVIAN RED successfully demonstrated the ability to stop hair loss and subsequently grow new hair.

“The final data is over 20% greater than the top-line data reported in September 2019,” said Brian Johnson, President of REVIAN Inc. “Higher amounts of hair growth in the first 4 months, the discovery of the statistically significant reduction of scalp itch, and more positive safety results for light therapy proves that REVIAN RED can redefine what is possible from an at-home hair loss treatment.”

Androgenetic alopecia, or pattern hair loss, affects approximately 50 million men and 30 million women suffering from hair loss in the United States.1

Male pattern hair loss is typically characterized by a receding hairline or balding of the crown, and female pattern hair loss appears as overall thinning or widening of the midline. Both men and women frequently suffer from scalp irritation and itch, establishing a need for treatments that improve overall scalp health.

Compelling Results

Adult men and women diagnosed with androgenetic alopecia were randomly assigned to a dual-wavelength, all-LED hair growth cap (REVIAN RED) or placebo cap (with no light therapy) for 10-minutes per day. Final results showed a mean improvement of 26.3 hairs/cm2 over the placebo cap among participants who were at least 80% compliant with the treatment protocol. Preliminary results had shown that participants assigned REVIAN RED had an average of 21.3 more hairs/cm2.

“We specifically designed this clinical trial with the rigour of a pharmaceutical trial,” said Rodney Sinclair, MD, professor of medicine at Melbourne University and principal investigator in the trial. “We used the same primary and secondary endpoints as were used in [the] finasteride and minoxidil studies. We used placebo caps. Participants and evaluators were blinded, and as an outcome, these results can be trusted.”

Reductions in Itching and Burning of the Scalp

As a part of the study, a quality-of-life questionnaire was used to assess itching, burning and stinging, irritation, and other patient-reported outcomes. Participants scored each question on a scale from 1 (never) to 5 (all the time). Statistically significant reductions were observed in patient-reported pruritus (itch) and burning/stinging compared to sham after 16 weeks of once-daily, at-home treatment.

“Scalp symptoms such as pruritus, burning, and irritation are extremely common complaints in the dermatological setting and can be frustrating for both the patient and dermatologist alike,” stated Dr Mark S. Nestor, Director of the Center for Clinical and Cosmetic Research and a Voluntary Professor at the Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine. “The clinical data showing a significant reduction in itching, burning, and irritation observed with this new class of LED light therapy that utilizes two wavelengths of light is extremely encouraging.”

The mechanisms of action for improved scalp symptoms are proposed to be the anti-inflammatory effects of nitric oxide (NO) released with the patented dual-wavelength light.

REVIAN Inc. is unaware of any previous reports of a reduction in “itchy scalp” with traditional single-colour laser-based devices used to treat androgenetic alopecia.

The dual-wavelength, all-LED REVIAN RED device demonstrated excellent safety. During the trial, there were no treatment discontinuations due to an adverse event and there were no device-related serious adverse events reported for any treatment arm.

About REVIAN RED

The REVIAN RED System is an FDA cleared, wireless wearable cap controlled by a mobile “smart” app that functions to provide a hair loss treatment for men and women using LED light. The patented dual-band, LED technology provides broader scalp coverage and better skin penetration than red lasers used in low-level laser therapy (LLLT). Dual wavelengths of LED light facilitate and accelerate scalp healing, allowing the body to renew cells associated with hair growth and retention.

Indications for use: The REVIAN RED System is indicated to treat androgenetic alopecia and to promote hair growth in males who have Norwood-Hamilton classifications of IIa–V patterns of hair loss and to treat androgenetic alopecia and promote hair growth in females who have Ludwig-Savin Scale I-1 to I-4, II-1, II-2 or frontal patterns of hair loss; both with Fitzpatrick Skin Types I–IV.

About REVIAN Inc.

REVIAN Inc is a medical technology innovator dedicated to stimulating the body’s natural processes to rejuvenate hair and skin with light.

We create products that precisely deliver light and allow people to experience its regenerative potential in the convenience of their own home. We are committed to partnering with health care providers and other caring professionals to deliver meaningful results backed by scientific data.

For more information, visit www.revian.com.

REVIAN Inc. is headquartered in Durham, is an operating subsidiary of KNOW Bio LLC and was formerly known as PhotonMD Inc.

Reference

https://ghr.nlm.nih.gov/condition/androgenetic-alopecia#statistics

REVIAN® Presents Leading Clinical Trial Results for New Hair Loss Treatment

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Revian announces patent for LED hair-loss prevention tech

REVIAN Presents Leading Clinical Trial Results for New Hair Loss Treatment

REVIAN Presents Leading Clinical Trial Results for New Hair Loss Treatment

REVIAN Inc – a medical technology company dedicated to stimulating the body’s natural processes to rejuvenate hair and skin with light – is excited to announce that final data from a randomized, double-blind study of the REVIAN RED hair growth system was presented at the 2020 Winter Clinical Dermatology Conference – Hawaii®.

The data is now available on the REVIAN website following the presentation at the conference. In this clinical trial, REVIAN RED successfully demonstrated the ability to stop hair loss and subsequently grow new hair.

“The final data is over 20% greater than the top-line data reported in September 2019,” said Brian Johnson, President of REVIAN Inc. “Higher amounts of hair growth in the first 4 months, the discovery of the statistically significant reduction of scalp itch, and more positive safety results for light therapy proves that REVIAN RED can redefine what is possible from an at-home hair loss treatment.”

Androgenetic alopecia, or pattern hair loss, affects approximately 50 million men and 30 million women suffering from hair loss in the United States.1

Male pattern hair loss is typically characterized by a receding hairline or balding of the crown, and female pattern hair loss appears as overall thinning or widening of the midline. Both men and women frequently suffer from scalp irritation and itch, establishing a need for treatments that improve overall scalp health.

Compelling Results

Adult men and women diagnosed with androgenetic alopecia were randomly assigned to a dual-wavelength, all-LED hair growth cap (REVIAN RED) or placebo cap (with no light therapy) for 10-minutes per day. Final results showed a mean improvement of 26.3 hairs/cm2 over the placebo cap among participants who were at least 80% compliant with the treatment protocol. Preliminary results had shown that participants assigned REVIAN RED had an average of 21.3 more hairs/cm2.

“We specifically designed this clinical trial with the rigour of a pharmaceutical trial,” said Rodney Sinclair, MD, professor of medicine at Melbourne University and principal investigator in the trial. “We used the same primary and secondary endpoints as were used in [the] finasteride and minoxidil studies. We used placebo caps. Participants and evaluators were blinded, and as an outcome, these results can be trusted.”

Reductions in Itching and Burning of the Scalp

As a part of the study, a quality-of-life questionnaire was used to assess itching, burning and stinging, irritation, and other patient-reported outcomes. Participants scored each question on a scale from 1 (never) to 5 (all the time). Statistically significant reductions were observed in patient-reported pruritus (itch) and burning/stinging compared to sham after 16 weeks of once-daily, at-home treatment.

“Scalp symptoms such as pruritus, burning, and irritation are extremely common complaints in the dermatological setting and can be frustrating for both the patient and dermatologist alike,” stated Dr Mark S. Nestor, Director of the Center for Clinical and Cosmetic Research and a Voluntary Professor at the Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine. “The clinical data showing a significant reduction in itching, burning, and irritation observed with this new class of LED light therapy that utilizes two wavelengths of light is extremely encouraging.”

The mechanisms of action for improved scalp symptoms are proposed to be the anti-inflammatory effects of nitric oxide (NO) released with the patented dual-wavelength light.

REVIAN Inc. is unaware of any previous reports of a reduction in “itchy scalp” with traditional single-colour laser-based devices used to treat androgenetic alopecia.

The dual-wavelength, all-LED REVIAN RED device demonstrated excellent safety. During the trial, there were no treatment discontinuations due to an adverse event and there were no device-related serious adverse events reported for any treatment arm.

About REVIAN RED

The REVIAN RED System is an FDA cleared, wireless wearable cap controlled by a mobile “smart” app that functions to provide a hair loss treatment for men and women using LED light. The patented dual-band, LED technology provides broader scalp coverage and better skin penetration than red lasers used in low-level laser therapy (LLLT). Dual wavelengths of LED light facilitate and accelerate scalp healing, allowing the body to renew cells associated with hair growth and retention.

Indications for use: The REVIAN RED System is indicated to treat androgenetic alopecia and to promote hair growth in males who have Norwood-Hamilton classifications of IIa–V patterns of hair loss and to treat androgenetic alopecia and promote hair growth in females who have Ludwig-Savin Scale I-1 to I-4, II-1, II-2 or frontal patterns of hair loss; both with Fitzpatrick Skin Types I–IV.

About REVIAN Inc.

REVIAN Inc is a medical technology innovator dedicated to stimulating the body’s natural processes to rejuvenate hair and skin with light.

We create products that precisely deliver light and allow people to experience its regenerative potential in the convenience of their own home. We are committed to partnering with health care providers and other caring professionals to deliver meaningful results backed by scientific data.

For more information, visit www.revian.com.

REVIAN Inc. is headquartered in Durham, is an operating subsidiary of KNOW Bio LLC and was formerly known as PhotonMD Inc.

Reference

https://ghr.nlm.nih.gov/condition/androgenetic-alopecia#statistics

REVIAN® Presents Leading Clinical Trial Results for New Hair Loss Treatment

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REVIAN Names President to Commercialize Medical Grade LED Light Therapy for Hair Growth

REVIAN Names President to Commercialize Medical Grade LED Light Therapy for Hair Growth

REVIAN Names President to Commercialize Medical Grade LED Light Therapy for Hair Growth

PhotonMD, Inc., a technology company dedicated to the advancement of light-based medical products, today announced the addition of a top executive from the dermatology industry to the company’s leadership team. Brian Johnson has joined the Company as President of the REVIAN business unit and will lead the commercialization efforts including sales, marketing and professional relations for the company’s aesthetic products based on breakthrough medical grade LED light technology.

REVIAN’s product pipeline includes recently launched REVIAN® RED, the first and only all-LED wearable cap for the treatment of androgenetic alopecia (“pattern hair loss”). In a randomized, double-blind, placebo-controlled trial of REVIAN RED, 10-minute once-daily treatment successfully demonstrated the ability to stop hair loss and grow new hair.

Full clinical trial results are expected to be published in a peer-reviewed medical journal early next year. This treatment provides an effective alternative to topical agents and oral prescription drugs.

“With all of the advancements in medicine, androgenetic alopecia shouldn’t be a skin disease that patients just have to ‘live with.’ We fundamentally believe that light can be used to put an end to hair loss,” states Mr. Johnson.

Brian Johnson brings three decades of sales and marketing leadership in companies ranging in size from large pharma companies like Novartis to microcap Novan, Inc. The majority of his commercial dermatology experience included roles at Johnson & Johnson, Medicis Pharmaceutical Corporation and Galderma Laboratories, LLC where he served as Vice President of Prescription Marketing and Chief Digital Officer. At Galderma, he and his team quadrupled sales by launching category leaders in acne, psoriasis, and rosacea, including Epiduo®, Clobex® and Oracea®.

“For some men and women living with hair loss, the impact on their quality of life and well-being can be devastating,” he continued. “Dermatology healthcare providers and other professionals spend more time with this condition than anyone, so our strategy will be to utilize those existing relationships to integrate REVIAN RED into routine care. Compliance is an important component of the treatment regimen, and our mobile app was designed to help users stay on schedule. This cloud-based platform technology also provides us some unique opportunities in the future as we aim to make this device mainstream for the 70 to 80 million sufferers throughout the United States,” concluded Mr. Johnson.

About REVIAN RED

The REVIAN RED System is an FDA cleared, wireless wearable cap controlled by a mobile “smart” app. The rechargeable battery-operated cap functions to provide a hair loss treatment for men and women using medical grade LED light. The patented dual-band, LED technology provides broader scalp coverage and better skin penetration than red lasers used in low level laser therapy (LLLT). Dual wavelengths of LED light facilitate and accelerate scalp healing, allowing the body to renew cells associated with hair growth and retention.

Indications for use: The REVIAN RED System is indicated to treat androgenetic alopecia and to promote hair growth in males who have Norwood-Hamilton classifications of IIa–V patterns of hair loss and to treat androgenetic alopecia and promote hair growth in females who have Ludwig-Savin Scale I-1 to I-4, II-1, II-2 or frontal patterns of hair loss; both with Fitzpatrick Skin Types I–IV.

About REVIAN

REVIAN was created to stimulate the body’s natural processes and rejuvenate hair and skin with light. Our team develops products that precisely deliver light and allow patients to experience its regenerative potential in the convenience of their own home. We are committed to partnering with health-care providers and other professionals to deliver their patients meaningful results, backed by scientific data. For more information, visit www.revian.com.

The REVIAN team is headquartered in Durham, NC, and functions as a business unit of PhotonMD, Inc., an operating subsidiary of KNOW Bio, LLC.

REVIAN® Names President to Commercialize Medical Grade LED Light Therapy for Hair Growth

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