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Bald Is Beautiful

Bald Men Perceived As More Attractive

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Bald Men Perceived As More Attractive, Dominant, Study Says

According to a new study, bald really is beautiful.

Researchers at the University of Pennsylvania have released the results of a survey that found that men who have shed their hair are more attractive.

The study was composed of three major tests given to students on campus. Male and female students were asked to rate photos of men according to attractiveness, confidence, and dominance.
Some of the photos also digitally removed hair from some of the pictures to show the same person with and without their locks.

According to the researchers, the bald men won out in all three categories. The study also says men who willingly ditch their hair are perceived as more appealing because they’ve gone against the traditional norms associated with hair and vitality.

“Choosing to dispense with one’s hair is arguably a form of nonverbal behavior, a form of expression which communicates information about the self otherwise difficult to observe,” researchers write.

‘‘Anyone can be confident with a full head of hair. But a confident bald man—there’s your diamond in the rough.’’ — Larry David

The findings also claim that bald men, being perceived as more dominant, will do better in business and economically overall. Based on their study, researchers at Penn also suggest that men beginning to lose their hair just let it happen.

“Instead of spending billions each year trying to reverse or cure their hair loss, the counter-intuitive prescription of this research to men experiencing male pattern baldness is to shave their heads.”

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Aclaris Therapeutics hair loss

Aclaris Therapeutics Patents for Treating Hair Loss Disorders

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Aclaris Therapeutics (ACRS) Granted Two U.S. Patents Covering JAK Inhibitors for Treating Hair Loss Disorders

Aclaris Therapeutics, Inc today announced that the United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 9,737,469 and U.S. Patent No. 9,730,877, which are directed to methods related to the use and administration of certain janus kinase (JAK) inhibitors for treating hair loss disorders.

U.S. Patent No. 9,730,877 covers the use of various JAK inhibitors, including tofacitinib, baricitinib, ruxolitinib and decernotinib, to treat androgenetic alopecia, also known as male/female pattern hair loss.

Experienced by 70% of men and 40% of women at some point in their lives, androgenetic alopecia is a genetic disorder and the most common cause of hair loss. The ‘877 Patent contains 22 claims and expires in November 2031.

U.S. Patent No. 9,737,469 covers the use of baricitinib for inducing hair growth and for treating hair loss disorders such as alopecia areata and androgenetic alopecia.

Additional issued claims pertain to methods of using baricitinib to treat particular phenotypes of alopecia areata, as well as to treat other hair loss disorders. The ‘469 Patent contains 10 claims and expires in November 2031.

These newly allowed patents are owned by The Trustees of Columbia University in the City of New York and exclusively licensed to Aclaris, and are the latest U.S. patents to issue in connection with Aclaris’ JAK drug development program for hair loss disorders.

“We are extremely pleased with the continued development of the patent portfolio we exclusively licensed from Columbia. These new issuances continue to expand the breadth and depth of our JAK inhibitor intellectual property portfolio covering methods of use for certain JAK inhibitors for the treatment of hair loss disorders.

The issuance of these patents is another successful step in the development of a robust patent portfolio relating to JAK inhibition and hair loss,” said Dr. Neal Walker, President and Chief Executive Officer of Aclaris.

Aclaris has exclusively licensed several patents and patent applications involving novel selective JAK 1/3 inhibitors, including a patent portfolio from Rigel Pharmaceuticals, Inc. that covers Aclaris’ product candidates ATI-50001 and ATI-50002, which are oral and topical formulations, respectively, also being developed as potential treatments for alopecia areata.

Additionally, Aclaris has exclusively licensed a patent portfolio from Columbia University directed to methods of using JAK inhibitors for the treatment of alopecia areata, androgenetic alopecia, and other dermatological conditions.

This portfolio includes the recently issued U.S. patents discussed above, as well as an issued U.S. patent directed to methods of treating alopecia areata, androgenetic alopecia and other hair loss disorders by administering ruxolitinib and issued patent claims in Japan directed to pharmaceutical compositions comprising ruxolitinib, baricitinib or other JAK inhibitors for use in treating alopecia areata, androgenetic alopecia and other hair loss disorders.

About Aclaris Therapeutics, Inc.

Aclaris Therapeutics, Inc. is a dermatologist-led biopharmaceutical company focused on identifying, developing and commercializing innovative and differentiated therapies to address significant unmet needs in medical and aesthetic dermatology.

Aclaris is focused on large, underserved market segments with no FDA-approved medications or where treatment gaps exist.  Aclaris is based in Malvern, Pennsylvania and more information can be found by visiting the Aclaris website at www.aclaristx.com.

Cautionary Note Regarding Forward-Looking Statements

Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as “believe”, “expect”, “may”, “plan,” “potential,” “will,” and similar expressions, and are based on Aclaris’ current beliefs and expectations. These forward-looking statements include expectations regarding the development of Aclaris’ product candidates focused on JAK inhibition for the treatment of hair loss disorders, including Aclaris’ intellectual property strategy. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements. Risks and uncertainties that may cause actual results to differ materially include uncertainties inherent in the conduct of clinical trials, Aclaris’ reliance on third parties over which it may not always have full control, risks associated with maintaining its intellectual property portfolio and other risks and uncertainties that are described in Aclaris’ Annual Report on Form 10-K for the year ended December 31, 2016, Aclaris’ Quarterly Report on Form 10-Q for the quarter ended June 30, 2017, and other filings Aclaris makes with the SEC from time to time.

These documents are available under the “Financial Information” section of the Investors page of Aclaris’ website at http://www.aclaristx.com. Any forward-looking statements speak only as of the date of this press release and are based on information available to Aclaris as of the date of this release, and Aclaris assumes no obligation to, and does not intend to, update any forward-looking statements, whether as a result of new information, future events or otherwise.

Garni hair loss

Successful Hair Re-Growth Product Is Now Available In The United States

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Successful Hair Re-Growth Product Is Now Available In The United States

BariLour Inc. announced the launch of their successful Garni Hair Serum for Men and Women. The product has been proven to help stop hair loss in 92% of users, and has been shown to help provide re-growth and growth of healthy hair.

“We are proud to launch the all-natural Garni Hair Serum for Men and Women here in the United States,” said Vaz Khachatryan, CEO of BariLour Inc. “It was really important for us to have an all-natural product that can help men and women address their fine or thinning hair.”

Garni Hair Serum for Men and Women has been a big success internationally – in large part due to the ingredients which come from one of the purest places on earth in Armenia.

“Our customers tell us that they love the fact that it’s easy to use, they don’t have to wait several hours to wash and use again, and they’ve found that it works,” said Khachatryan. “Hair thinning and loss can be very emotional. We are proud to provide a solution.”

Hair loss is not just an issue affecting men. More than 40% of women will experience hair loss after age 40.

About all natural Garni Hair Serum for Men and Women: Garni Hair Serum has been widely accepted and successful internationally prior to coming to the United States in National Hair Loss Awareness Month.

It has been clinically proven, is easier to use than other hair re-growth and thinning products, and is all natural. Garni is prepared according to an old unique recipe which comprises extracts of natural herbs from an ecologically pure zone of Armenia.

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P1P, a cell-regenerating substance developed in Korea

Why do hair loss prevention and treatment industries pay attention to P1P

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Why do hair loss prevention and treatment industries pay attention to P1P, a cell-regenerating substance developed in Korea?

P1P (Phytosphingosine 1 Phosphate), a cell-regenerating substance developed in Korea, which is thought to be effective in overcoming hair loss caused by stress, is now drawing attention from the domestic hair loss prevention and treatment industry.

It was learned that ‘S1P(Sphingosine 1 Phosphate),’ a substance found minimally in the blood, helps to regenerate cells in the body and prevent aging, is effective in preventing necrocytosis due to stress. However, the idea did not lead to the development of products owing to expensive prices.

Under such circumstances, a team of doctors at KAIST continued to delve into the matter in search of its analogs, and succeeded in identifying P1P.

By applying P1P to cosmetic and hair loss prevention products, ‘P1P’, a ‘phytosia’ and aesthetic skin care brand, was launched into the market, earning a patent associated with prevention and treatment of hair loss, and a composition for hair growth.

From this connection, a skin and hair society in Europe announced the effect of P1P on the mechanism of hair growth.

Dr. Myung-Joon Choi of KAIST who released P1P said, “While studies are actively under way on the application of P1P worldwide, the projects have met a limitation, that is, it is prohibitively expensive, making it a project of low marketability.

Under such circumstances, I am so glad that we managed to open the possibility of commercializing the substance since we have secured a technology of synthesizing the substance for mass production. We will continue to work steadily on the project to introduce better products.”

The P1P substance developed by Korea’s phyto-associated industries are expected to find extensive applications in the domestic medical and bio-industry for stem cell culture technology and the treatment of degenerative neurological diseases.

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hair loss

New treatment hope for thinning hair and hair loss

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New treatment hope for thinning hair and hair loss

There are many causes for hair thinning and hair loss. Your dermatologist can help determine the exact cause and, in turn, help develop the appropriate treatment plan.

The most common type of hair loss, called androgenetic hair loss (alopecia), is also known as male pattern and female pattern hair loss (also alopecia). Alopecia is the medical term for hair loss of any type.

Androgenetic alopecia (AGA) is inherited and dependent on certain hormones (androgens) to happen. AGA is where men’s hair tends to thin out and they lose hair in the front corners of the forehead, top of head, and crown of scalp.

In women, female pattern hair loss produces a generalized thinning all over the head to where the scalp becomes visible. AGA is a cosmetic concern and also produces significant psychological and psychosocial stress in those who are losing their hair.

Currently, there are two FDA-approved treatments for androgenetic alopecia. For men, there are topical minoxidil and oral finasteride. There is one FDA-approved treatment for AGA in women, topical minoxidil. Unfortunately, neither works perfectly.

The good news

There is a new treatment for AGA, not yet FDA-approved, called platelet-rich plasma (PRP), and it is producing some very compelling results in some patients without any adverse side effects. PRP is a blood plasma concentration of a patient’s own platelets, growth factors and cytokines.

PRP is not new. It has been used in various medical applications for over 20 years. It has been a favorite of orthopedic surgeons to assist in the body’s own regenerative repair of joints and tendons.

Other studies suggest PRP can work well in soft tissue injuries and in cases of degenerative bone disease. Oral surgeons and plastic surgeons have used it to promote healing. In my dermatology practice, I have successfully used PRP to treat aging skin, wrinkles, dark circles under the eyes and, as reported in this article, for the treatment of hair loss.

There are hundreds of professional athletes who have successfully been treated with PRP for sports injuries. Some well-known athletes who have been treated with  PRP include Kobe Bryant, Tiger Woods, Derick Jeter, Alex Rodriguez, Tony Parker, Derrick Rose, David Ortiz, Sidney Rice, Bartolo Colon, Rafael Nadal and Maria Sharapova, just to name a few.

What is PRP?

A small amount of the patient’s own blood is collected and spun down in a centrifuge. This results in a layer that is rich in platelets, growth factors and cytokines. This layer is collected and mixed with calcium carbonate, which causes an additional release of growth factors and cytokines from the platelets.

prp hair loss

This rich mixture of the patient’s own platelets, growth factors and cytokines is then injected back into the patient’s targeted area to enhance tissue healing and regeneration. It is both safe and natural. I tell patients PRP is “just you, helping you.”

This rich mixture of the patient’s own platelets, growth factors and cytokines can also stimulate hair growth in cases of AGA. There have been numerous reports of successfully treating hair loss with PRP. Recently, Dr. Mysore et al. reported a study of 60 patients, 49 men and 11 women, ages 25-45.

In this study, the participants were injected with PRP approximately every six weeks for a total of four sessions.  Remarkably, 70 percent of the participants reported good to very good regrowth. Only 15 percent of the participants had no regrowth at all. In fact, 36 percent of the participant had “very good to excellent” regrowth.

PRP is a simple and safe procedure to treat male and female pattern hair loss. The procedure has been used hundreds of times without any major side effects. PRP can be used as a solo treatment for hair loss or used in combination with other hair loss treatments.

Although not yet FDA-approved for the treatment of androgenetic hair loss, successful reports are mounting, and the approval may be coming in the not-too-distant future. Until then, many people are trying PRP “off-label” to treat hair loss.

Of course, more studies need to be conducted to confirm these early, hopeful reports. Although PRP may not be the perfect treatment or cure for hair loss, it does give doctors another treatment option, and that is always welcomed.

If you have tried other treatments for male or female pattern hair loss without good results, talk to your dermatologist about participating in a PRP trial for AGA. You only have your hair to lose!

Charles E. Crutchfield III, MD is a board certified dermatologist and Clinical Professor of Dermatology at the University of Minnesota Medical School. He also has a private practice in Eagan, MN.

He received his M.D. and Master’s Degree in Molecular Biology and Genomics from the Mayo Clinic. He has been selected as one of the top 10 dermatologists in the United States by Black Enterprise magazine.

Dr. Crutchfield was recognized by Minnesota Medicine as one of the 100 Most Influential Healthcare Leaders in Minnesota. He is the team dermatologist for the Minnesota Twins, Vikings, Timberwolves, Wild and Lynx. Dr. Crutchfield is an active member of both the American and National Medical Associations.

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hair loss

Restoring Lives as well as Hair

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Restoring Lives as well as Hair

Losing your hair can be a bewildering and frightening experience and can sometimes make you feel like you are losing your mind.

You only have to Google ‘hair loss remedies’ to see that it is something that affects millions of people worldwide; the internet is bursting with home remedies, advice and medical opinion.

According to the NHS one in three people will suffer from hair loss at any one time.

But what happens when you have tried every herbal remedy going?

A leading hair loss expert based in West Yorkshire said there many reasons why hair loss is becoming more common.

Sean-Jordan Baruch runs a hair loss clinic in Pudsey and became fascinated by hair loss solutions after suffering his own problems.

“We are experiencing an increase of many forms of hair loss. It may be androgenetic alopecia, post pregnancy hair loss, medication hair loss or thinning of the hair. We have an answer for most hair loss issues within our centre.”

He said herbal remedies were good for the scalp but useless in thickening the hair itself.

“Many people clutch at straws and opt for a herbal remedy to assist and things like castor oil/mustard oil/olive oil are very good for the scalp but won’t reverse thinning hair.”

He said the starting point was to identify the cause of hair loss as there are many reasons why hair falls out in the first place.

There are four main types of hair loss.

Alopecia areata is an autoimmune disorder in the skin that causes hair loss. This condition usually starts with one or more 50p-size bald circles on the scalp that usually range in size from a 1p piece to a 50p. These circles can move, multiply, grow, or go into remission for months or even years.

Traction alopecia is a fairly common type of hair loss and caused by pulling at hair follicles. Tight hair styles, hair pieces or braids woven into the existing hair can pull at hair follicles and eventually leave small bald spots on the scalp or visibly thin out hair.

Though it can often grow back, continued pressure over extended periods of time can cause permanent hair loss.

Alopecia totalis/universalis is one of the more serious types of hair loss, and is similar to alopecia areata in that it is an autoimmune disorder that causes the immune system to attack hair follicles.

However, rather than the smaller circles found with areata, totalis sufferers lose hair all over their heads while universalis sufferers experience hair loss on the entire body.

The precise causes are still unknown and, though many kinds of treatments are used by doctors, none have been shown to be specifically effective.

Telogen effluvium is more a description than a condition and is when more hair is in the dormant phase (telogen) than the growth phase (anagen). It appears as shedding or diffuse thinning over the scalp.

This type of hair loss can be very unpredictable and could be related to several causes, including hormonal imbalance. It can also happen after giving birth or possibly be triggered by high stress. It’s typically not permanent, and hair often grows back once stress decreases or hormones regain a healthy balance.

Androgenetic or androgenic alopecia (“male-pattern baldness,” “female-pattern baldness”) is more to do with genetic predisposition and family history. Androgenic alopecia is seen in both men and women. The hair loss in men is often faster, earlier onset, and more extensive.

Mr Baruch said: “Remember that not all hair loss is the same and genetics, hormones, and the environment can all play a role.”

He became fascinated by hair loss treatments after suffering his own hair loss issues and looked into hi-tech solutions.

“I have had all our procedures at the clinic so I can offer first hand advice which is very important.”

One of the most popular procedures offered by hair loss clinics is LLLT – a low level laser therapy.

Mr Baruch said: “I have used LLLT to arrest my hair fall, I used a non-surgical hair transplant on my crown for some years which looked amazing. When I introduced Baruch hair transplants to my company I underwent a pain-free procedure namely FUE (follicular Unit Extraction) where you have individual follicles removed from the back of my head and implanted in the crown. I now need no other procedures to maintain my hair.”

He’s been working in the hair loss business for 15 years now.

It isn’t simple vanity. Hair loss is hugely distressing for men and women.

“Our client base is approximately 65 per cent male and 35 per cent female at present. Hair loss is a major problem for many people globally.

“Hair is a crowning glory to most women. Many celebrities have come forward in the past 10 years and knocked years off their looks and a massive boost of confidence undergoing non-surgical or surgical transplants at our clinic.”

Mr Baruch said boosting confidence in people was one of the most rewarding aspects of his work.

“I have always strived to improve people’s lives and found restoring people;s hair gave me the same sense of achievement. I have worked in the hair loss industry for 15 years and expect many more years to come. We assist children, men and women and change their lives around to regain confidence and become happy with their lives.”

And he said he ensured that treatment was always affordable.

“We offer many treatments ranging from £55 up to £10,000.”

He even has a trademark catchphrase payment plan called ‘Pay as you Grow™’.

“We trademarked this in 2013 to allow patients to pay as they grow. This allows people on a lower income to join the programme.

“We carry a 98 per cent success rate with laser therapy (4,000 clients), 100 per cent with non-surgical grafting and 100 per cent for surgery. We are a registered medical Hair Transplant Centre with the Care Quality Commission which regulates health care providers and all doctors are GMC registered.”

BY ANILA BAIG (copyright NEWSQUEST/BRADFORD LIFE MAGAZINE)

Contact Information

Yorkshire Hair Replacement Clinic Ltd

yorkshirehairreplacementclinic.co.uk

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hair loss

Hair loss not just a mens issue

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Hair loss not just a men’s issue: How surgery changed a Valley woman’s life

Almost every woman cares about her hair, and when it’s not right, it can mess with your confidence.

Not too long ago, Ginette Weiner wasn’t happy with her reflection.

“I couldn’t look in the mirror anymore at my hair,” said Weiner.

The 65-year-old woman says time was taking its toll.

“I can live with a few wrinkles, but when I started looking in the mirror and started having balding where I could actually see my scalp on the sides, and my hairline was receding, and my enormous forehead was getting even larger, it made me feel horrible. It made me feel old,” Weiner describes.

Nearly as many women experience hair loss and thinning as men, but not a lot of women are talking about it.

“I don’t know why. Hair loss makes you feel guilty and ashamed as if there’s something wrong with you. People would look at me with a lot of sympathy, but not saying much,” explains Weiner.

She combed through a ton of information and found the answer to her problem.

“I came across Dr. Keene and I was just totally blown away. She’s a bonafide surgeon. She publishes articles. She’s the real deal,” Weiner said.

Dr. Sharon Keene is an internationally-recognized pioneer and highly-regarded expert in the hair transplant industry.

“When a woman has had only a small area of the hairline affected or receding back and if it’s not caused by inflammation, and it’s caused just by the gradual aging process, those are very good candidates for surgery, as are women who’ve had some forms of cosmetic surgery,” Dr. Keene explained.

Dr. Keene transplanted Weiner’s hair from the back of her head to the front along her hairline. For Ginette Weiner, it was a transformation both inside and out.

“It has given me back my life, and I know that sounds extreme, but that is exactly the way I feel,” describes Weiner.

Dr. Keene says women with thinning hair make up 10 percent of her practice at Physician’s Hair Institute in Phoenix and Tucson. She says the embarrassing condition is complicated and can be caused by a number of different factors.

“It can be caused by metabolic abnormalities, hormonal abnormalities, nutritional deficiencies, medications. It can be caused by stress, illness, or just a particular emotional stress,” Dr. Keene explained.

She says that’s why surgery can’t help every woman and she warns about quick fixes and false promises from people who are not experts in hair restoration.

“It is a concern to those of us in the field that there are casual clinics popping up, promising to regrow hair for patients.
It’s very important that anyone who is wanting an assessment and wanting to treat their hair loss, go to somebody who’s actually knowledgeable about the field, not simply someone who owns a machine that they can use to redistribute hair.

Dr. Keene says the fallout from these types of clinics is a loss of trust and a waste of time and money.

“I’ve had patients who’ve come to my office and told me they spent thousands of dollars on lasers, and it didn’t do a thing for them. I’m very disappointed when I hear that,” says Dr. Keene.

For women like Ginette Weiner, the right doctor and the right treatment made all the difference in the world.

“I can look in the mirror now. I feel good about my hair. They’re growing like mad. It’s a perfectly natural hairline, and it’s thick. It’s amazing,” said Weiner.

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